Meta-inflammation and cardiometabolic disease in obesity: Can heat therapy help?

How Food Industries Can Help in Preventing Childhood Obesity and Metabolic Syndrome?

The association between obesity, cardiometabolic disease biomarkers, and innate immunity-related inflammation in Canadian adults

INTRODUCTION Obesity is associated with a state of chronic inflammation, and increased cardiometabolic disease risk. The present study examined the relationship between body mass index (BMI) and cardiometabolic and inflammatory biomarkers among normal weight, overweight, and obese Canadian adults. METHODS Subjects (n = 1805, aged 18 to 79 years) from the Canadian Health Measures Survey (CHMS)...

Toll-like receptor, lipotoxicity and chronic inflammation: the pathological link between obesity and cardiometabolic disease.

The epidemic growth in the prevalence of obesity has made the impact of metabolic syndrome on cardiovascular events increasingly significant. Elevated visceral adiposity, the indispensable component of metabolic syndrome, is thought to play a primary role in the increasing incidence of cardiometabolic disorders. Importantly, obesity is not merely the simple expansion of adipose tissue mass; it ...

Controversies about sugars: results from systematic reviews and meta-analyses on obesity, cardiometabolic disease and diabetes

Fructose-containing sugars are a focus of attention as a public health target for their putative role in obesity and cardiometabolic disease including diabetes. The fructose moiety is singled out to be the primary driver for the harms of sugars due to its unique endocrine signal and pathophysiological role. However, this is only supported by ecological studies, animal models of overfeeding and ...

Obesity: can a new drug help?

Introduction Obesity is known to be a major health risk. The data here arise from a study which aimed to investigate whether or not a new drug, used as part of a regime of diet, exercise and drug treatment, could assist in weight reduction for obese individuals. Patients taking part in the study were healthy adults (aged 18 to 65 years) and were between 30% and 80% above their ideal body weight...